Plasma cytokines and chemokines differentiate between active and non-active tuberculosis infection
نویسندگان
چکیده
منابع مشابه
Cytokines and Chemokines in Mycobacterium tuberculosis Infection.
Chemokines and cytokines are critical for initiating and coordinating the organized and sequential recruitment and activation of cells into Mycobacterium tuberculosis-infected lungs. Correct mononuclear cellular recruitment and localization are essential to ensure control of bacterial growth without the development of diffuse and damaging granulocytic inflammation. An important block to our und...
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Introduction: Limited data are available on the relationship between nutritional status and tuberculosis. The aim of this study was to evaluate and compare the body mass index (BMI) and serum albumin level in patients with active tuberculosis (ATB) and latent tuberculosis (LTB). Materials and Methods: A cross-sectional study was conducted on 17 patients newly diagnosed with pulmonary TB who we...
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BACKGROUND The immunologic environment during HIV/M. tuberculosis co-infection is characterized by cytokine and chemokine irregularities that have been shown to increase immune activation, viral replication, and T cell dysfunction. METHODS We analysed ex vivo plasma samples from 17 HIV negative and 16 HIV pulmonary tuberculosis co infected cases using Luminex assay to see impact of HIV co-inf...
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Objective(s): Tuberculosis is one of the most important infectious diseases with high mortality rates worldwide, especially in developing countries. Interleukin17 (IL-17) is an important acquired immunity cytokine, which is mainly produced by CD4+TH17 cells. It can recruit neutrophils and macrophages to the infected site in the lungs. IL-23 is one of the most important inducers of IL-17. In the...
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Tuberculosis (TB) is an old disease representing a major public health problem globally. The current widely used tools are very long time since licensed and are inefficient in diagnosing and prognosing of tuberculosis infection and disease. A new diagnostic test which is sensitive, specific and rapid is urgently needed for timely detection, appropriated treatment response and control. Biomarker...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2013
ISSN: 1664-3224
DOI: 10.3389/conf.fimmu.2013.02.00289